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Home > Health Conditions > Digestive GI Health

HMF Replete Probiotic by Genestra (7 sachets) (NON- RETURNABLE)

1 Box of 7 sachets
HMF Replete Probiotic by Genestra (7 sachets) (NON- RETURNABLE)
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  • This item is non-returnable and non-refundable whether opened or not.
  • We do NOT recommend this product if you have intestinal yeast issue, or if you have severe GI issues. You must first start with a probiotic free of FOS such as
    HMF Intensive by Genestra.

HMF Replete Probiotic by Genestra

Intensive-level Probiotic Formula

  • 150 billion CFU per sachet
  • FOS Prebiotic included
  • Ideal for vegans
  • Convenient Sachet format

HMF Replete is a highly concentrated probiotic formula in sachets which provides strains of proprietary human-sourced Lactobacillus acidophilus, Lactobacillus salivarius, Bifidobacterium bifidum and Bifidobacterium animalis subsp. lactis along with fructooligosaccharides (FOS) in high concentrations to ensure rapid establishment and dominance of probiotic cultures in the gastrointestinal tract.

HMF Replete is the highest potency HMF product containing a minimum of 150 billion CFU of L. acidophilus, L. salivarius, B. bifidum, B. animalis lactis, and in each packet.  It also includes prebiotic oligosaccharides to stimulate growth of beneficial bacteria in the digestive system. Each of the different strains attach in different areas of the epithelial tissue in the intestinal tract (small and large intestines).

High concentrations in these sachets are to ensure rapid establishment and dominance of probiotic cultures in the gastrointestinal tract, especially during and following antibiotic therapy, chemotherapy and radiation therapy. Major imbalances of friendly bacteria may result in severe abdominal discomfort, extreme fatigue and yeast infections. This probiotic is a microbial replacement program for the gastrointestinal tract intended for 7 to 14 days depending on the level of need.

Supplementation of Lactobacilli and Bifidobacteria will crowd out unwanted bacteria by repopulating the gastrointestinal tract. Lactobacillus salivarius, which triggers an anti-inflammatory response, has been demonstrated to be beneficial in acute and severe intestinal disturbances, dysbiosis, and inflammatory bowel diseases such as Irritable Bowel Syndrome, Crohn's and ulcerative colitis. This product can be used in autoimmune conditions such as multiple sclerosis, lupus and rheumatoid arthritis, but keep in mind that the probiotics activate the immune system so you may want to try a lesser potency probiotic from the HMF probiotic line before taking this product so not to over-stimulate the immune system ( consult the nutritionist here for guidance).

Pharmax and GENESTRA BRANDS™ are probiotic science and innovation leaders, with over 20+ years of proven experience and an ongoing commitment to incorporate the safest and most effective strains that reflect the latest evidence-based research from human trials. Their probiotics are human-sourced strains, proven in human clinical trials and cover a comprehensive product range. These Human Micro Flora (HMF) are human-derived strains and are the original product line of their kind in North America.  Most other probiotics are made from animal or dairy strains and may not adhere as well to the human gastrointestinal tract.

Supplement Facts
Serving Size ½ Sachet (10 g)/
Servings per Container 14

Each Serving Contains

Calories                                                                            25 calories
Total Carbohydrate                                                           9 g
  Dietary Fiber                                                                   5 g
  Sugars                                                                            4 g

Probiotic Consortium                                                        75 billion CFU*
  Lactobacillus acidophilus (CUL-60)
  Lactobacillus acidophilus (CUL-21)
  Bifidobacterium bifidum (CUL-20)
  Bifidobacterium animalis subsp. lactis (CUL-34)
  Lactobacillus salivarius (CUL-61)
Fructooligosaccharides (FOS)                                         5g
CFU - Colony Forming Units

Other ingredients: Apricot powder

Recommended Adult Dosage: In a glass, add water to ½ sachet of HMF Replete and mix. Take once daily with a meal, or as recommended by your healthcare practitioner.

Total potency per sachet may be up to 170 billion CFU's.

Hypoallergenic Product. 

Guaranteed to contain no added wheat, starch, gluten, soy, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products. Ideal for vegans.

If you have an immune compromised condition, do not use. If you are experiencing nausea, fever, vomiting, bloody diarrhea or severe abdominal pain, consult your healthcare practitioner prior to use. If symptoms of digestive upset occur, worsen or persist beyond three days, discontinue use and consult your healthcare practitioner.

Quality Assurance Safety-sealed for your protection and for product freshness. Do not use if sachet is opened. Refrigeration of this product is recommended to prolong shelf life. Label claim will be met if unrefrigerated up to three months.

Read customer questions and answers about HMF Probiotics on our blog.

Additional product info:

The human microbiota influences the state of health of our gastrointestinal tract. Although much of our initial microbiota is adopted from our mothers, its final composition and diversity is determined by environmental factors. Extensive experimental and clinical evidence indicates that the westernized diet, rich in animal products and low in complex carbohydrates, plus the overuse of antibiotics and underuse of breastfeeding, leads to a heightened inflammatory potential of unfavorable microbiota (1).

Other factors such as environmental pollutants and stress may also alter the fragile intestinal ecosystem equilibrium, which can lead to physiological changes in the intestinal environment, disrupting the functions of the gut microbiota. Autoimmune, allergic and bacterial infections have all been associated to gut dysbiosis (8). Bifidobacterium bifidum and Lactobacillus lactis are found more commonly in the composition of the intestinal flora of non-allergic children (6),(7). In addition, HMF Replete is indicated for dysbiosis(8), and symptoms associated with irritable bowel syndrome (IBS) (2) which has also been shown in human double-blind, placebo-controlled clinical studies, at a core consortium of 25 billion CFU to:

• Reduce the risk of Clostridium difficile associated diarrhea in hospitalized patients (5)
• Significantly improved the Symptom Severity Score of patients suffering from irritable bowel syndrome (IBS) and scores for quality of life, days with pain and satisfaction with bowel habit compared to placebo, when taken for 8 weeks (2)
• Daily administration of Lactobacillus salivarius to healthy adults has shown to improve gut microbiota and different parameters related to immune response (9).

HMF Replete will crowd out yeast and other undesirable organisms which result from use of antibiotics, chemotherapy, oral contraceptives, and hormone replacement therapy. Also helpful for chronic parasitic and fungal infections as well as Candida overgrowth.

Intensive Phase
Take 1 packet daily (1/2 packet twice daily) after meal or snack, mixed in water or in smoothie or off the spoon for 7-14 days.

Clinical Considerations
  1. During and Post-antibiotic therapy
  2. Acute intestinal upset
  3. Candidiasis (as a follow up after no FOS probiotic has been used)
  4. Digestive disturbances (bloating, gas)
  5. Parasitic infections
  6. Chronic Fatigue Syndrome
  7. Bowel problems (constipation, diarrhea, IBS)
  8. Skin problems

Intermediate Phase
Take 1/2 packet daily after meal or snack, mixed in water or in smoothie or off the spoon.

Clinical Considerations
  1. General illness
  2. Stressful life style
  3. Parasitic infections
  4. Digestive problems (bloating, gas)
  5. Constipation
  6. Excessive alcohol consumption
  7. Bowel problems (constipation, diarrhea, IBS)
  8. Chronic Fatigue Syndrome
  9. Candidiasis (as a follow up after no FOS probiotic has been used)

  10. Click the link to read more about HMF Probiotics, shipping and storage.

  1. Greer JB, O'Keefe SJ. Microbial induction of immunity, inflammation, and cancer. Front Physiol. 2011 Jan 26;1:168
  2. Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, Barker ME, Corfe BM. “Clinical trial: a multistrain probiotic preparation significantly reduces the symptoms of irritable bowel syndrome in a double-blind placebo-controlled trial.” Alimentary Pharmacology & Therapeutics. 2008. 29(1):97-103.
  3. Plummer SF, Garaiova I, Sarvotharn T, Cottrell SL, LeScouiller S, Weaver MA et al. Effects of probiotics on the composition of the intestitinal microbiota following antibiotic therapy. Int J Antimicrob Agents. 2005; 26(1):69-74.
  4. Madden JA, Plummer SF, Tang J, Garaiova I, Plummer NT, Herbison T, et al. Effects of probiotics on preventing disruption of the intestinal microflora following antibiotic therapy: a double-blind, placebo-controlled pilot study. Int Immunopharmacol. 2005; (6): 1091-7.
  5. 5. Plummer, S., Weaver, M.A., Harris, J.C., Dee, P. and Hunter, J. “ Clostridium difficile pilot study: effects of probiotics supplementation on the incidence of C.difficile diarrhea.” International Microbiology. 2004; 7(1):59-62.
  6. Ozdemir O. Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data. Clin Exp Immunol. 2010 Jun;160(3):295-304.
  7. Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM, Ji GE. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immunol. 2010 Mar;21(2 Pt 2):e386-93.
  8. Prakash S, Rodes L, Coussa-Charley M, Tomaro-Duchesneau C. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics. 2011;5:71-86.
  9. Sierra S, Lara-Villoslada F, Sempere L, Olivares M, Boza J, Xaus J. Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults. Anaerobe. 2010 Jun;16(3):195-200.
Summer Shipping/Delivery Schedule JUN - SEPT.
(Saturday delivery is not available)
(Orders received after 1pm EST will be processed the next day)

Monday by 1pm EST

Ground shipping - delivery on Thursday
2nd day shipping - delivery on Wednesday
Overnight - delivery on Tuesday

Tuesday by 1pm EST

Ground shipping - delivery on Friday
2nd day shipping - delivery on Thursday
Overnight - delivery on Wednesday

Wednesday by 1pm EST - only 2nd day & overnight orders will be processed.
Orders received after 1pm or which have ground shipping, will be held until the following Monday.

2nd day - delivery on Friday
Overnight - delivery on Thursday

Thursday by 1pm EST - only Overnight orders will be processed.
Orders received after 1pm or which have ground shipping or 2nd day, will be held until the following Monday.

Overnight - delivery Friday


Should I request a cold pack?
From June-Sept, we recommend requesting an cold pack at check out as the cold pack helps keep the interior package temperature cooler during the hot travel months.  Between Sept - May requesting a cold pack is optional, but you may want to do so if shipping to a hot climate (over 85 degrees F).
After extensive product testing with the freeze drying technology performed by Genestra, it was concluded that the cold pack did not make a difference during shipping since the product potency was still well over 100% label claim when shipped with ice or no ice. The manufacturer states that it is less necessary to ship the HMF products with an cold pack for these reasons: 1. Genestra has added in >40% more probiotic than what the label guarantees per bottle. For example, HMF Forte is guaranteed to have 10 billion CFU's per serving, but there are 18-20 billion present at time of manufacturing and it is kept frozen until shipping. 2. The probiotics to last up to 3 months at room temperature holding their GUARANTEED minimum potency on label! 3. You will receive your HMF probiotic directly from the manufacturer or our distributor in about 3-5 days. This product is very fresh and has not been sitting around on our shelves.

How do I travel with my HMF probiotics?
We highly recommend you take your probiotics with you on all trips and vacations since their potency will last for up to 3 months at room temperature un-refrigerated. But, when possible and if convenient, we recommend you store your probiotics in the freezer or refrigerator, especially if you plan to preserve freshness of your product for months or years.

Average Rating
Customer Reviews
Worth a try 3/25/2013
Reviewed by Rachel from Robson Valley, BC.
Easy and pleasant to take. I cannot definitively prove that it did anything for me. However, taking the following into consideration, I would take it again:- 1). There is irrefutable evidence that gut biota have a profound effect on one's health. 2). Grocery store probiotics contain only a very small number of bacteria relative to the trillions in your gut and the bacteria are from non-animal sources and only a single species. The Genestra products contain a much greater quantity and the bacteria are cultured from human sources and contain several species. Some authorities believe that everyone's gut has a distinct gut flora composition to which it will usually eventually return after any perturbation. It seems to be a matter of faith whether taking probiotics orally will change anything in the long term. But if you think it will, or if you are suffering such that you are ready to try probiotics, then Genestra products are the way to go unless you want to try a faecal inoculation from a healthy human donor. The small numbers of single non-human bacteria in grocery store probiotic drinks and yogurts will not do anything for you whereas Genestra probiotics just might.

Highly recommended for extra sensitive systems 2/26/2013
Reviewed by Jacinte from Victoria.
This product has been most effective at neutralizing the nasty side effects I seem to always experience with antibiotics. I am not able to use a lot of over the counter probiotics but this one in particular seems to agree with me no problem ... thanks Genestra

HMF Replete Does Not Disappoint! 9/6/2012
Reviewed by Great Product! from Vancouver, BC.
This product is amazing. I've been having issues with my bladder and HMF replete helped me with the bladder symptoms which the doctors all say I do not have a bladder infection but I seem to have all the symtoms.

Fixed thrush for me an my nursing baby 12/8/2011
Reviewed by Tina M. from Phoenixville, PA.
Thank you, your product was great & helped to clear a thrush issue I was having with nursing my infant who also had thrush. I am happy to say I don't need any further assistance!

Great product 11/4/2011
Reviewed by Edith from Brighton, ON.
This product was recommended to us by a holistic veterinarian for our dog to prevent side effects of cancer treatments. It seems to work well. Super fast shipping.

Excellent PB 8/7/2011
Reviewed by Paola from Kingston, ON.
Great quality and very effective! Shipping was so fast!

works well! 4/28/2011
Reviewed by Sue from Victoria.
Shipping time is excellent, and the product is very effective for digestive regulation.

Great product, fast shipping 3/30/2011
Reviewed by LDrgon from Vancouver, BC.
This probiotic works fantastic and does not compare to others. Recently helped a fried avoid the sideaffects of antibiotics. Great to find a supplier that ships and reduce trips to the naturopath!

HMF replete 3/8/2011
Reviewed by Monika from Cambridge, Ontario.
This is the favorite probiotic for myself and my family. We all have IBD issues and this is the only product that has worked consistently for us.

HMF Replete 2/24/2011
Reviewed by Janice from Ontario, Canada.
I'm a believer! My guts LOVE your probiotic, as do I!

HMF Replete 2/16/2011
Reviewed by LEW from Nova Scotia.
Have used this product for years after I finish a course of antibiotiics. Words wonderfully.

HMF Replete 8/24/2010
Reviewed by paul worby from tofield, ab.
Great product!

HMF Replete 8/5/2010
Reviewed by B.B. from Regina.
I bought it for someone else.. I'll get back to you on the results.

Good product 2/9/2010
Reviewed by Ricki from Rockwood, ON.
I really think this product did some good for my gut. Customer service is excellent.

HMF Replete 4/2/2008
Reviewed by Dave from Ontario, Canada.
This is, far and away, the best probiotic supplement available on the market today. The price is reasonable, the service is good. I''m really glad I ordered from Rockwell

Worked for my yeast infection! 4/14/2007
Reviewed by Heather from Columbia, MO.
I really like this product, I was amazed at how it worked so well for my yeast infection.

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